Are eligible AD clinical trial participants more likely to have spousal 
caregivers than adult children caregivers?
 
   Lead Investigator:    Joshua Grill
   Institution      :    UCLA
   E-Mail           :    JGrill@mednet.ucla.edu
   Proposal ID      :    153


   Publications:


1  Grill JD,  Monsell S , Karlawish J
   Are patients whose study partners are spouses more likely to be eligible for Alzheimer's disease clinical trials?
   Journal Article  Dement Geriatr Cogn Disord,33:334-340,2012,PMC3477789

   PUBLISHED





   Proposal Description:
   Data Plan:    I. Examine study partner relationships for all NACC participants that meet criteria for probable or possible AD dementia (initial visit only)          II. Examine study partners of trial eligible subjects    Provide the same outcome measures when limiting the population to those eligible for a hypothetical clinical trial (criteria below). Only participants meeting all of the inclusion and none of the exclusion criteria should be included.              Statistical plan:    Perform descriptive statistics on the dementia population and compare by Chi square or Mann Whitney, as appropriate, the study partner groups   Spousal   Adult child   Other (combining Form A2 Item 8 [3, 4, 5, 6, and 7])  Determine the proportion of dementia subjects who would be eligible for a clinical trial    Meets ALL of the inclusion criteria, does not meet ANY exclusion criteria  Compare by Chi square the proportion of the groups that are eligible for a trial   Spousal   Adult child   Other (combining Form A2 Item 8 [3, 4, 5, 6, and 7])  Perform descriptive statistics on the trial eligible populations and compare by Chi square or Mann Whitney, as appropriate, to the greater population (Part 1) for each of the study partner groups   Spousal   Adult child   Other (combining Form A2 Item 8 [3, 4, 5, 6, and 7])  Repeat 1-4 using only two groups: Spousal vs Adult Child